Friday, September 12, 2014

9/12/2014: The Pickwickian Evil that Ails the Honorable Minister

Despite his inane and some kind-of insane doings, Syed Mohsin Ali, the honorable minister of Bangladesh government who claims to have shared smoke and/or smoked alongside the father of our all-powerful sitting Prime Minister, deserves some credit to bring the not-so-peculiar Pickwickian issue to the fore; this issue, indeed, is a public health scourge, yet not a single newsman has written anything about up to this time. May be we lack the astute sense of Dickensian observation or we are too busy vilifying the ministers distasteful testiness.

Dickens’s “The Pickwick Paper” described a young Joe who was generous in build, had a love for gastronomical delights and had an uncanny ability to fell asleep anywhere. One hundred twenty years later in 1956, Dr. Burwell and his colleagues described this medical entity in a medical case report titled “Extreme Obesity Associated With Hypoventilation: A PICKWICKIAN SYNDROME”. This was case of a 51-year-old obese business executive weighing over 260 pounds and standing only five foot 5. He was suffering from obesity, fatigue and daytime somnolence. Somnolence was quite disabling that during a poker game he failed to take the opportunity when dealt with a hand of three aces and two kings! Such was the peril … however, Syed Mohsin Ali, I bet, given his very busy and successful life is doing quite well …

We have new name for this condition. We call it OBSTRUCTICVE SLEEP APNEA, a disorder, usually occurring in obese persons, in which, during sleep, lax tissue crowds the access to the breathing tube leading to frequent micro-awakenings and a state of chronic sleep deprivation leading daytime somnolence to catch up. Loud snoring is a very common associated feature. There is another kind of less common sleep apnea that can happen in non-obese persons too; it is called CENTRAL SLEEP APNEA, because, here the brain is at fault. In this article, we will focus on the more prevalent obstructive type.

What causes sleep apnea is a query that defies a clear or precise answer. During the wakeful hours the active tone of the throat muscles keeps the airway wide open. During sleep the absence of wakeful tone causes the muscles to relax with subsequent throat narrowing. Normally this is not a problem; however, in persons with obstructive sleep apnea there is partial or complete obstruction. Enough air does not flow in the lung, oxygen level in blood drops, that in turn wakes the brain up which help tighten the upper airway muscles and open the wind pipe. Normal breathing starts again, often with a loud snort or choking sound.

This oft repeated drop on blood oxygen level and reduced quality of sleep can trigger the release of stress hormones which, in turn, increases the risk of other nefarious maladies like high blood pressure, heart attack, stroke and irregular heart rhythm. When untreated, sleep apnea also alters the normal energy utilization leasing further worsening obesity and the risk of diabetes.

Yes, it is a nasty disease and commonly it comes with a loud bell – snoring, which can prove sore in relationship too. However, its symptoms are not as stealthy as early hypertension or diabetes or cancer. Excessive day time sleepiness, fatigue, poor concentration, morning headache etc. should prompt a doctor’s visit and subsequent diagnostic work up including a possible polysomnogram (PSG) that does simultaneous measurement of brain activity, eye movements and, hear rate and blood pressure.

Once diagnosed, treatment, cumbersome though, is very effective. However, losing weight, avoiding alcohol and stopping tobacco smoking can be an intial thumbs up ...And this brings us back to our honorable minister Syed Mohsin Ali, who happened to an avid smoker too. Sir, it’s time to stop smoking and see a doctor …